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[1]刘守德,刘华梅,周 莉,等. 多粘类芽孢杆菌的研究进展 [J].武汉工程大学学报,2022,44(03):237-243.[doi:10.19843/j.cnki.CN42-1779/TQ.202202013]
 LIU Shoude,LIU Huamei,ZHOU Li,et al.Research Progress of Paenibacillus Polymyxa[J].Journal of Wuhan Institute of Technology,2022,44(03):237-243.[doi:10.19843/j.cnki.CN42-1779/TQ.202202013]
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多粘类芽孢杆菌的研究进展 (/HTML)
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《武汉工程大学学报》[ISSN:1674-2869/CN:42-1779/TQ]

卷:
44
期数:
2022年03期
页码:
237-243
栏目:
综述
出版日期:
2022-06-30

文章信息/Info

Title:
Research Progress of Paenibacillus Polymyxa
文章编号:
1674 - 2869(2022)03 - 0237 - 07
作者:
刘守德12刘华梅2周 莉2黄 芳2徐 广2武若楠1王小华13胡国元*1
1. 武汉工程大学环境生态与生物工程学院,湖北 武汉 430205;
2. 武汉科诺生物科技股份有限公司,湖北 武汉 430074;
3. 武昌理工学院生命科学学院,湖北 武汉 430223
Author(s):
LIU Shoude12 LIU Huamei2 ZHOU Li2 HUANG Fang2 XU Guang2 WU Ruonan1WANG Xiaohua13 HU Guoyuan*1
1. School of Environmental Ecology and Bioengineering, Wuhan Institute of Technology, Wuhan 430205, China;
2. Wuhan Kernel Bio-tech Co., Ltd, Wuhan 430074, China;
3. School of Life Science, Wuchang University of Technology, Wuhan, 430223, China

关键词:
多粘类芽孢杆菌功能基因代谢活性物质应用
Keywords:
Paenibacillus polymyxafunctional genomemetabolic active substance application

分类号:
Q939.97
DOI:
10.19843/j.cnki.CN42-1779/TQ.202202013
文献标志码:
A
摘要:
多粘类芽孢杆菌是一类兼具生物防治和促生长作用的植物根际细菌,在农业、工业及医药等领域广泛应用。综述了多粘类芽孢杆菌的基因组,代谢活性物质和应用研究。重点论述了抗生素及植物促激素合成相关基因,胞外多糖、抗菌物质、植物激素等代谢活性物质的研究,并列举了多粘类芽孢杆菌在农业、工业及医药等领域的应用实例。该菌的常规选育和发酵过程研究较多,但其工程菌株和生防机理的研究较少。通过利用基因编辑、代谢组学、宏基因组学和蛋白质组学等手段对该菌进行功能基因的改造、发酵工艺的优化与放大及其与植物和土壤微生物间互作机理的解析等,有望提升多粘类芽孢杆菌的产品性能。

Abstract:
Paenibacillus polymyxa(P. polymyxa),a kind of plant rhizosphere bacteria with both biological control and growth promoting effects, is widely used in agriculture, industry and medicine.This paper reviews the genome, metabolically active substances and application research of P. polymyxa. The paper focuses on the study of gene research relating to the synthesis of antibiotics and plant hormone-promoting,metabolic active substances research such as exopolysaccharides, antibacterial substances and phytohormone and lists their application progresses in agriculture, industry and medicine. There are many reports on conventional breeding and fermentation process of this strain, but few studies on engineering strain and biocontrol mechanism.By means of gene editing, metabolomics, metagenomics and proteomics, the functional genes of P.polymyxa are modified, the fermentation process is optimized and amplified, and the interaction mechanism with plant and soil microorganisms is analyzed, which is expected to improve the product performance of P. polymyxa.

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备注/Memo

备注/Memo:
收稿日期:2022-02-23
基金项目:武汉科诺生物科技股份有限公司研发项目(NC599)
作者简介:刘守德,硕士研究生,工程师。E-mail:[email protected]
*通讯作者:胡国元,博士,教授。E-mail:[email protected]
引文格式:刘守德,刘华梅,周莉,等. 多粘类芽孢杆菌的研究进展[J]. 武汉工程大学学报,2022,44(3):237-243.
更新日期/Last Update: 2022-06-29